Publications

1. Jackson, S. G., Zhang, F., Chindemi, P., Junop, M. S. & Berti, P. J. (2009) Biochemistry 48:11715-11723 Evidence for Kinetic Control of Ligand Binding and Staged Product Release in MurA (Enolpyruvyl UDP-GlcNAc Synthase)-Catalyzed Reactions

2. Berti, P. J. & Chindemi, P. (2009) Biochemistry 48:3699-3707 Catalytic Residues and an Electrostatic Sandwich That Promote Enolpyruvyl Shikimate 3-Phosphate Synthase (AroA) Catalysis

3. McCann, J. A. B. & Berti, P. J. (2008) J. Am. Chem. Soc. 130:5789-5797 Transition State Analysis of the DNA Repair Enzyme MutY

4. McCann, J. A. B. & Berti, P. J. (2007) J. Am. Chem. Soc. 129:7055-7064 Transition State Analysis of Acid-catalyzed dAMP Hydrolysis

5. Clark, M. E. & Berti, P. J. (2007) Biochemistry 46:1933-1940 Enolpyruvyl Activation by Enolpyruvyl Shikimate 3-Phosphate Synthase

6. Zhang, F. & Berti, P. J. (2006) Biochemistry 45:6027-6037 Phosphate Analogues as Probes of the Catalytic Mechanisms of MurA and AroA, Two Carboxyvinyl Transferases

7. Loncke, P. G. & Berti, P. J. (2006) J. Am. Chem. Soc. 128:6132-6140 Implications of Protonation and Substituent Effects for C-O and O-P Bond Cleavage in Phosphate Monoesters

8. Berti, P. J. & McCann, J. A. B. (2006) Chem. Rev. 106:506-555 Toward a Detailed Understanding of Base Excision Repair Enzymes: Transition State and Mechanistic Analyses of N-Glycoside Hydrolysis and N-Glycoside Transfer

9. Mizyed, S., Oddone, A., Byczynski, B., Hughes, D. W., & Berti, P. J. (2005) Biochemistry 44:4011-4017 UDP-N-acetylmuramic acid (UDP-MurNAc) is a Potent Inhibitor of MurA (Enolpyruvyl-UDP-GlcNAc synthase)

10. Lee, J. K., Bain, A. D. & Berti, P. J. (2004) J. Am. Chem. Soc. 126:3769-3776 Probing the Transition States of Four Glucoside Hydrolyses with ¹³C Kinetic Isotope Effects Measured at Natural Abundance by NMR Spectroscopy.

11. Byczynski, B., Mizyed, S. & Berti, P. J. (2003) J. Am. Chem. Soc. 125:12541-12550 Non-enzymatic Breakdown of the Tetrahedral (α-Carboxyketal Phosphate) Intermediates of MurA and AroA, Two Carboxyvinyl Transferases. Protonation of Different Functional Groups Control the Rate and Fate of Breakdown.

12. McCann, J. A. B. & Berti, P. J. (2003) J. Biol. Chem. 278:29587-29592 Adenine Release is Fast in MutY-Catalyzed Hydrolysis of G:A and 8-oxo-G:A DNA Mismatches

13. Mizyed, S., Wright, J. E. I., Byczynski, B. & Berti, P. J. (2003) Biochemistry 42:6986-6995 Identification of the Catalytic Residues of AroA (Enolpyruvylshikimate 3-Phosphate Synthase) Using Partitioning Analysis

14. Berti, P. J., & Tanaka, K. S. E. (2002) Adv. Phys. Org. Chem. 37:239-314 Transition State Analysis Using Multiple Kinetic Isotope Effects: Mechanisms of Enzymatic and Non-enzymatic Glycoside Hydrolysis and Transfer

15. Chen, X.-Y., Berti, P. J. & Schramm, V. L. (2000) J. Am. Chem. Soc. 122:6527-6534 Transition State Analysis for Depurination of DNA by Ricin A-Chain

16. Chen, X.-Y., Berti, P. J. & Schramm, V. L. (2000) J. Am. Chem. Soc. 122:1609-1617 Ricin A-Chain: Kinetic Isotope Effects and Transition State Structure with Stem-Loop RNA

17. Berti, P. J. (1999) Methods Enzymol. 308:355-397 Determining Transition States from Kinetic Isotope Effects

18. Berti, P. J. & Schramm, V. L. (1999) Enzymatic Transition State Structures Constrained by Experimental Kinetic Isotope Effects in ACS Symposium Series No. 721/Transition State Modeling for Catalysis ; Trulhar, D. G., Morokuma, K., Eds.; American Chemical Society: Washington, D.C.; pp 473-488

19. Scheuring, J., Berti, P. J. & Schramm, V. L. (1998) Biochemistry 37:2748-2758 Pertussis Toxin: Transition State Structure for ADP-ribosylation of Recombinant G_iα1 Subunits

20. Berti, P. J., Blanke, S. R. & Schramm, V. L., (1997) J. Am. Chem. Soc. 119:12079-12088 Transition State Structure for the Hydrolysis of NAD⁺ Catalyzed by Diphtheria Toxin

21. Berti, P. J. & Schramm, V. L. (1997) J. Am. Chem. Soc. 119:12069-12078 Transition State Structure of the Solvolytic Hydrolysis of NAD⁺